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I think looking at the actual data from the one clinical study, there wasn't statistical significance until all three of the pieces of data were pulled together
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NMN treatment led to the upregulation of genes associated with energy‐related metabolic pathways such as oxidative phosphorylation, pyruvate metabolism, fatty acid metabolism, GSH metabolism, glycolysis/gluconeogenesis, fatty acid degradation, and valine, leucine, and isoleucine degradation in the ovaries of the mice in the aged group (Figure 5F), indicating an increase in energy‐related metabolic processes such as amino acid metabolism, lipid metabolism, and oxidative phosphorylation in aged mouse ovarian tissues following NMN treatment
